Publications:73
Thomas P Zwaka, MD, PhD
About Me
Dr. Zwaka’s research focuses on fundamental questions surrounding stem cell biology, including how to reverse the process of differentiation and “re-program” any given cell type into a pluripotent stem cell. Zwaka Lab website: https://www.zwakalab.org/
Language
English
Position
PROFESSOR | Stem Cell Biology And Regenerative Medicine
Research Topics
Apoptosis/Cell Death, Cell Biology, Developmental Biology, Embryology, Epigenetics, Gene Regulation, Gene Therapy, Stem Cells, Tissue Engineering, Transcription Factors, Transcriptional Activation and Repression
Multi-Disciplinary Training Areas
Development Regeneration and Stem Cells [DRS]
Education
MD PhD, University of Ulm
Postdoctoral, University of Wisconsin, Madison
Research
This project seeks to clarify the molecular function Ronin, a member of the THAP (Thanatos-associated domain-containing apoptosis-associated proteins) gene family, and its biochemical role in specific cell types as they change fates. We propose that Ronin (and other THAPs) mediate promoter-promoter interactions to regulate gene transcription in a cell type-specific manner.
Publications
Selected Publications
- Bats as instructive animal models for studying longevity and aging. Lisa Noelle Cooper, Mohammad Y. Ansari, Grace Capshaw, Alex Galazyuk, Amanda M. Lauer, Cynthia F. Moss, Karen E. Sears, Mark Stewart, Emma C. Teeling, Gerald S. Wilkinson, Rachel C. Wilson, Thomas P. Zwaka, Rena Orman. Annals of the New York Academy of Sciences
- Abortive infection of bat fibroblasts with SARS-CoV-2. Punam Bisht, Michael D. Gallagher, M. Inmaculada Barrasa, Julie Boucau, Alfred Harding, Marion Déjosez, Carlos Godoy-Parejo, Margaret E. Bisher, Giovanni de Nola, Abigail K.R. Lytton-Jean, Lee Gehrke, Thomas P. Zwaka, Rudolf Jaenisch. Proceedings of the National Academy of Sciences of the United States of America
- Advancing stem cell technologies for conservation of wildlife biodiversity. Ashlee M. Hutchinson, Ruth Appeltant, Tom Burdon, Qiuye Bao, Rhishikesh Bargaje, Andrea Bodnar, Stuart Chambers, Pierre Comizzoli, Laura Cook, Yoshinori Endo, Bob Harman, Katsuhiko Hayashi, Thomas Hildebrandt, Marisa L. Korody, Uma Lakshmipathy, Jeanne F. Loring, Clara Munger, Alex H.M. Ng, Ben Novak, Manabu Onuma, Sara Ord, Monique Paris, Andrew J. Pask, Francisco Pelegri, Martin Pera, Ryan Phelan, Benyamin Rosental, Oliver A. Ryder, Woranop Sukparangsi, Gareth Sullivan, Nicole Liling Tay, Nikki Traylor-Knowles, Shawn Walker, Antonia Weberling, Deanne J. Whitworth, Suzannah A. Williams, Jessye Wojtusik, Jun Wu, Qi Long Ying, Thomas P. Zwaka, Timo N. Kohler. Development (Cambridge)
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Below are financial relationships with industry reported by Dr. Zwaka during 2025 and/or 2026. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Founder/Co-Founder/Partner
- Paratus Sciences
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.