Tianliang Sun, PhD

About Me

Dr. Tianliang Sun has had long-lasting interest in understanding the cell-cell communication during physical or pathological conditions. His current research is centered around the mechanisms of liver regeneration and diseases. Combining state-of-art single cell profiling, spatial transcriptomics, lineage tracing and organoid CRISPR screening, he investigates the plasticity and heterogeneity in multicellular dynamics during liver homeostasis, regeneration and diseases progression.

To learn more about the Sun Lab, please visit our website: http://www.tianliangsunlab.com/

Language

English

Position

ASSISTANT PROFESSOR | Medicine, Liver Diseases

Research Topics

Aging, Autoimmunity, Biomedical Sciences, Cancer, Cancer Genetics, Cell Adhesion, Cell Biology, Cell Division, Cell Motility, Cell Transformation, Cellular Differentiation, Chemotaxis, Chromatin, Computational Biology, DNA Recombination, Developmental Biology, Drug Design and Discovery, Epigenetics, Epithelial Cells, Extracellular Matrix, Fibrosis, Gene Discovery, Gene Expressions, Gene Regulation, Gene Therapy, Gene editing, Genetics, Growth, Growth Factors and Receptors, Image Analysis, Imaging, Inflammation, Integrins, Knockout Mice, Lipid Signaling, Liver, Metabolism, Molecular Biology, Oxidative Phosphorylation, Oxidative Stress, Pharmacology, Protein Degradation, Protein Trafficking & Sorting, Receptors, Regeneration, Stem Cells, Transcriptional Activation and Repression, Transgenic Mice, Tumor Suppressor Genes, Tumorigenesis

Multi-Disciplinary Training Areas

Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS], Disease Mechanisms and Therapeutics (DMT)

Education

Ms, Shanghai Institutes for Biological Science, Chinese Academy of Science

PhD, Max-Planck-Institute for Heart and Lung Research

, Max-Planck-Institute for Heart and Lung Research

, Novartis Institutes for BioMedical Research

Awards

2024

Junior Faculty Award

ASIP

Research

Cell identity is a dynamic property that can be acquired or lost as cells interact with their environment. This dynamic cell plasticity plays a crucial role in maintaining tissue homeostasis, facilitating regeneration, and driving disease progression. The Sun lab is dedicated to unraveling the intricate mechanisms underlying the shaping of cell identity and how these processes contribute to the adaptation or promotion of physiological and pathological processes. Through our research efforts, we seek to gain deeper insights into the fundamental principles governing cell identity dynamics, with the ultimate goal of developing innovative strategies for therapeutic intervention in various disease states. Lab website: http://www.tianliangsunlab.com/