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Profile image of Tristan Shuman

    Tristan Shuman, PhD

    Education

    PhD, University of California, San Diego

    , University of California, Los Angeles

    Awards

    2020

    Shah Research Scholar

    Friedman Brain Institute

    2018

    CURE Taking Flight Award

    CURE Epilepsy

    2018

    AES Junior Investigator Award

    American Epilepsy Society

    2018

    Nash Family Scholar

    Friedman Brain Institute

    2016

    AES Young Investigator Award

    American Epilepsy Society

    2015

    AES Grass Young Investigator Award

    American Epilepsy Society

    2014

    Epilepsy Foundation Postdoctoral Fellowship

    Epilepsy Foundation

    Research

    Alzheimer’s disease (AD) is a form of dementia characterized by memory loss and progressive cognitive impairments. Memory impairments in AD increase with age and are linked to hyperexcitability, circuit remodeling, and impaired interneuron function. However, it remains unclear how changes in interneuron function contribute to cognitive deficits. My lab is using in vivo electrophysiology with silicon probes to examine how hippocampal interneuron function is altered in AD model mice and investigate whether network dysfunction in young, pre-symptomatic mice can predict future memory impairments.