
Vahram Haroutunian, PhD
About Me
Dr. Haroutunian joined the faculty at The Mount Sinai School of Medicine in the summer of 1982 and is Professor of Psychiatry and Neuroscience. Dr. Haroutunian came to Mount Sinai after completing a postdoctoral training program at Princeton concentrating on research in development in aging. His research interests since joining the Mount Sinai faculty have centered on the neurobiology of Alzheimer’s disease, successful aging and schizophrenia. He directs the Mount Sinai NIH Neurobiobank and the Alzheimer’s Disease Research Center Neuropathology Core. Dr. Haroutunian is Principal Investigator on over 10 different NIH grants and contracts. He is also the Associate Director for Research for the Veterans Administration Mental Illness Research and Education Clinical Center. Dr. Haroutunian’s research interests include gene and protein expression at the single cell level in health and disease; development of novel approaches for the study of the human brain, including laser capture microdissection, digital neuropathology, application of artificial intelligence to reveal pathological and neuroanatomical features not immediately appreciated by the human eye. Dr. Haroutunian’s lab collaborates extensively the laboratories of Dr. Panagiotis Roussos, Dr. Bin Zhang, and Dr. Pavel Katsel.
Language
English
Position
PROFESSOR | Psychiatry, PROFESSOR | Neuroscience
Research Topics
Aging, Alzheimer's Disease, Gene Expressions, Myelination, Neurotransmitters, Post-Transcriptional Processing, Prefrontal Cortex, Psychiatry, RNA, Schizophrenia
Multi-Disciplinary Training Areas
Neuroscience [NEU]
Education
PhD, Kent State University
, Princeton University
Publications
Selected Publications
- Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution. John F. Fullard, Prashant NM, Donghoon Lee, Deepika Mathur, Karen Therrien, Aram Hong, Clara Casey, Zhiping Shao, Marcela Alvia, Stathis Argyriou, Tereza Clarence, David Burstein, Sanan Venkatesh, Pavan K. Auluck, Lisa L. Barnes, David A. Bennett, Stefano Marenco, Biao Zeng, Hui Yang, Zhenyi Wu, Xinyi Wang, Daifeng Wang, Fotios Tsetsos, Karen Therrien, Collin Spencer, Maxim Signaevsky, Lyra Sheu, Madeline R. Scott, Genadi Ryan, Vivek G. Ramaswamy, Christian Porras, Milos Pjanic, Jennifer Monteiro Fortes, Colleen A. McClung, Nicolas Y. Masse, Athan Z. Li, Mikaela Koutrouli, Roman Kosoy, Steven P. Kleopoulos, Seon Kinrot, Saniya Khullar, Pavel Katsel, Ting Jin, Pengfei Dong, Kiran Girdhar, Vahram Haroutunian, Gabriel E. Hoffman, Georgios Voloudakis, Jaroslav Bendl, Panos Roussos. Scientific data
- Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing. Jack Humphrey, Erica Brophy, Roman Kosoy, Biao Zeng, Elena Coccia, Daniele Mattei, Ashvin Ravi, Tatsuhiko Naito, Anastasia G. Efthymiou, Elisa Navarro, Claudia De Sanctis, Victoria Flores-Almazan, Benjamin Z. Muller, Gijsje J.L.J. Snijders, Amanda Allan, Alexandra Münch, Reta Birhanu Kitata, Steven P. Kleopoulos, Stathis Argyriou, Periklis Malakates, Konstantina Psychogyiou, Zhiping Shao, Nancy Francoeur, Chia Feng Tsai, Marina A. Gritsenko, Matthew E. Monroe, Vanessa L. Paurus, Karl K. Weitz, Tujin Shi, Robert Sebra, Tao Liu, Lot D. de Witte, Alison M. Goate, David A. Bennett, Vahram Haroutunian, Gabriel E. Hoffman, John F. Fullard, Panos Roussos, Towfique Raj. Nature Genetics
- Multiomic single-cell profiling identifies critical regulators of postnatal brain. Tereza Clarence, Jaroslav Bendl, Xuan Cao, Xinyi Wang, Shiwei Zheng, Gabriel E. Hoffman, Alexey Kozlenkov, Aram Hong, Marina Iskhakova, Manoj K. Jaiswal, Sarah Murphy, Alexander Yu, Vahram Haroutunian, Stella Dracheva, Schahram Akbarian, John F. Fullard, Guo Cheng Yuan, Donghoon Lee, Panos Roussos. Nature Genetics