Publications:246
Willem J Mulder, PhD
About Me
Willem Mulder, Ph.D., a biomedical engineer with a background in nanochemistry, is Professor of Radiology and Professor of Oncological Sciences at Icahn School of Medicine at Mount Sinai (ISMMS) in New York, as well as Professor of Precision Medicine at the Eindhoven University of Technology (TU/e), The Netherlands. Mulder obtained an M.Sc. in Chemistry from the Utrecht University (2001) and a Ph.D. in Biomedical Engineering from Eindhoven University of Technology (2006).
Mulder pioneered the exploitation of nanomaterials as highly tunable immunotherapeutics and molecular imaging agents. His research focuses on (nano-)immunotherapy and precision imaging in cardiovascular diseases, cancer and transplantation. Mulder established library technology, encompassing nanomaterials derived from natural lipoproteins (nanobiologics), that allows meticulously designing targeted immunotherapies. When appropriately designed, such nanobiologics can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics.
Mulder has published more than 150 scientific publications in top scientific journals, including Nature Nanotechnology, Nature Reviews Drug Discovery, Nature Communications, Science Translational Medicine, Immunity, etc. His H-index is 62 and his work has been cited more than 11.000 times. Mulder is the principal investigator of multiple National Institutes of Health grants. In 2013, he received the Vidi grant, while in 2018 and the Vici grant from the Dutch Science Foundation (NWO).
Language
English
Position
PROFESSOR | Diagnostic, Molecular and Interventional Radiology
Education
M.Sc., Utrecht University
Ph.D., Eindhoven University of Technology
Publications
Selected Publications
- Immuno-imaging in solid organ transplantation. Rianne J.F. Maas, Iris Versteeg, Lisanne C. de Jong, Zahi Fayad, Erik H.J.G. Aarntzen, Willem J.M. Mulder, Abraham J.P. Teunissen, Raphaël Duivenvoorden. American Journal of Transplantation
- Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells. Mirre M. Trines, Daniek Hoorn, Stijn R.J. Hofstraat, Robby C. Zwolsman, Tom Anbergen, Iris Versteeg, Yuri van Elsas, Jeroen Deckers, Merel M.A. Hendrikx, Teun Kleuskens, Youssef B. Darwish, Gijs W.B. Ros, Sjoerd F. Dijkstra, Bram Priem, Matt Timmers, P. Michel Fransen, Maarten J. Pouderoijen, Bas F.M. de Waal, E. W. Meijer, Thijs J. Beldman, Yohana C. Toner, Ewelina Kluza, Willem J.M. Mulder, Henk M. Janssen, Roy van der Meel. Advanced Materials
- Systemically inducing trained immunity overcomes solid tumors’ immunosuppressive microenvironment. Bram Priem, Lisa Willemsen, Tom Anbergen, Yuri van Elsas, Jeroen Deckers, David P. Schrijver, Stijn R.J. Hofstraat, Iris V. Messing, Jazz Munitz, Dionne Honing, Geoffrey Prévot, Yohana C. Toner, Judit Morla, William Wang, Anna Ranzenigo, Isabella Sirchia, Tomas Post, Raphaël Duivenvoorden, Ewelina Kluza, Glenn A.O. Cremers, Joost H.C.M. Kreijtz, Carlos Pérez-Medina, Mandy M.T.van Leent, Abraham J.P. Teunissen, Roy van der Meel, Yi Zhou, Chris Glass, Jordi Ochando, Leo A.B. Joosten, Zahi A. Fayad, Romana T. Netea-Maier, Mihai G. Netea, Menno P.J.de Winther, Thijs J. Beldman, Arjan W. Griffioen, Willem J.M. Mulder. Science advances
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Mulder has not yet completed reporting of industry relationships or has no industry relationships to report.
Mount Sinai’s faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.