Mount Sinai Doctors
Yuxin Liu, MD, PhD
Anatomic Pathology and Clinical Pathology
About Me
Dr. Yuxin Liu is a Professor of Pathology and Director of the Gynecologic Pathology Service and Fellowship Program. Her academic focus centers on HPV-associated cervical and anal cancers, with a strong commitment to advancing translational research in these areas.
Together with Drs. Michael Gaisa and Keith Sigel in the Department of Medicine, they lead a productive anal cancer research program within the Mount Sinai Health System (PPAC). She serves as co-PI on several NCI-funded clinical trials, including the SWAN study—the first anal cancer screening trial focused on women with a history of cervical precancer or cancer.
From 2021 to 2023, Dr. Liu served on the Board of Directors of the International Anal Neoplasia Society (IANS), an organization dedicated to the prevention and treatment of anal cancer. She currently directs the HPV Pathology Core Laboratory for the AIDS Malignancy Consortium (AMC) and provides central pathology review for multiple AMC-sponsored clinical trials conducted both nationally and internationally.
Dr. Liu is also the lead author of the cervical SIL section in the 6th edition of the WHO Classification of Female Genital Tumors.
IANS pathology website: https://www.iansoc.org/Pathology
SWAN study: https://www.swan-study.org/
PPAC: https://www.mountsinai.org/patient-care/iam/services/anal-cancer-prevention-program
Publications:
1. Stier EA, Clarke MA, Deshmukh AA, Wentzensen N, Liu Y, Poynten IM, Cavallari EN, Fink V, Barroso LF, Clifford GM, Cuming T, Goldstone SE, Hillman RJ, Rosa-Cunha I, La Rosa L, Palefsky JM, Plotzker R, Roberts JM, Jay N. International Anal Neoplasia Society's consensus guidelines for anal cancer screening. Int J Cancer. 2024 Jan 31. PMID: 38297406.
2. Yuxin Liu, Bhardwaj S, Sigel K, Winters J, Terlizzi J, Gaisa MM. Anal cancer screening results from 18-to-34-year-old men who have sex with men living with HIV. Int J Cancer. 2024 Jan 1;154(1):21-27. PMID: 37728489.
3. Yuxin Liu, Kevin Weiss, Andrés Ramírez Zamudio, Monica Prasad Hayes, Mona Saleh, Michael M Gaisa, Keith Sigel. Primary Anal Cancer Screening Results from 381 Women Living with HIV. J Infect Dis. 2023;227(8):932-938. PMID: 36196502.
4. Yuxin Liu, W Glenn McCluggage, Teresa M Darragh, et al. p16 Immunoreactivity Correlates with Morphological Diagnosis of HPV-associated Anal Intraepithelial Neoplasia: A study of 1,000 Biopsies. Am J Surg Pathol. 2021;45(11):1573-1578. PMID: 34231547
5. Michael M Gaisa, Keith M Sigel, Ashish A Deshmukh, Volha Lenskaya, Courtney A Chan, Richard Silvera, John Winters, Yuxin Liu. Comparing Anal Cancer Screening Algorithms Using Cytology and HPV DNA Testing in Three High-risk Populations. J Infect Dis. 2021;224(5):881-888. PMID: 33388757.
6. Yuxin Liu, Monica Prasad Hayes, Eric M. Ganz, Juan Lucas Poggio, Volha Lenskaya, Threshia Malcolm, Ashish Deshmukh, Wenxin Zheng, Keith Sigel and Michael M. Gaisa. HIV-Positive Women with Anal HSIL: A study of 153 Cases with Long-Term Anogenital Surveillance. Modern Pathology 2020;33(8):1589-1594. PMID: 32152521
7. Yuxin Liu, W Glenn McCluggage, Teresa M. Darragh, Wenxin Zheng, Jennifer M. Roberts, Kay J. Park, Pei Hui, Morgan Blakely, Keith Sigel, Michael M. Gaisa. Classifying AIN 2 Based on LAST Recommendations: Interobserver Agreement Among Experienced Pathologists. Am J Clin Pathol. 2021;18;155(6):845-852. PMID: 33210115
8. Michael Gaisa, Yuxin Liu, Ashish A. Deshmukh, Kimberly Stone, Keith Sigel. Electrocautery Ablation of Anal High-grade Squamous Intraepithelial Lesions: Effectiveness and Key Factors Associated with Outcomes. Cancer. 2020;126(7):1470-1479. PMID: 31977082
9. Yuxin Liu, Keith M Sigel, William Westra, Melissa R Gitman, Wenxin Zheng, Michael M Gaisa. HIV-infected Patients with Anal Cancer Precursors: Clinicopathological Characteristics and HPV Subtype Distribution. Dis Colon Rectum 2020;63(7):890-896. PMID: 32168092
10. Ashish A Deshmukh, Ryan Suk, Meredith S Shiels, Kalyani Sonawane, Alan G Nyitray, Yuxin Liu, Michael M Gaisa, Joel M Palefsky, Keith Sigel. Recent trends in squamous cell carcinoma of the anus incidence and mortality in the United States, 2001-2015. J Natl Cancer Inst. 2020;112(8):829-838. PMID: 31742639
Language
Position
Hospital Affiliations
- Mount Sinai Queens
- The Mount Sinai Hospital
About Me
Dr. Yuxin Liu is a Professor of Pathology and Director of the Gynecologic Pathology Service and Fellowship Program. Her academic focus centers on HPV-associated cervical and anal cancers, with a strong commitment to advancing translational research in these areas.
Together with Drs. Michael Gaisa and Keith Sigel in the Department of Medicine, they lead a productive anal cancer research program within the Mount Sinai Health System (PPAC). She serves as co-PI on several NCI-funded clinical trials, including the SWAN study—the first anal cancer screening trial focused on women with a history of cervical precancer or cancer.
From 2021 to 2023, Dr. Liu served on the Board of Directors of the International Anal Neoplasia Society (IANS), an organization dedicated to the prevention and treatment of anal cancer. She currently directs the HPV Pathology Core Laboratory for the AIDS Malignancy Consortium (AMC) and provides central pathology review for multiple AMC-sponsored clinical trials conducted both nationally and internationally.
Dr. Liu is also the lead author of the cervical SIL section in the 6th edition of the WHO Classification of Female Genital Tumors.
IANS pathology website: https://www.iansoc.org/Pathology
SWAN study: https://www.swan-study.org/
PPAC: https://www.mountsinai.org/patient-care/iam/services/anal-cancer-prevention-program
Publications:
1. Stier EA, Clarke MA, Deshmukh AA, Wentzensen N, Liu Y, Poynten IM, Cavallari EN, Fink V, Barroso LF, Clifford GM, Cuming T, Goldstone SE, Hillman RJ, Rosa-Cunha I, La Rosa L, Palefsky JM, Plotzker R, Roberts JM, Jay N. International Anal Neoplasia Society's consensus guidelines for anal cancer screening. Int J Cancer. 2024 Jan 31. PMID: 38297406.
2. Yuxin Liu, Bhardwaj S, Sigel K, Winters J, Terlizzi J, Gaisa MM. Anal cancer screening results from 18-to-34-year-old men who have sex with men living with HIV. Int J Cancer. 2024 Jan 1;154(1):21-27. PMID: 37728489.
3. Yuxin Liu, Kevin Weiss, Andrés Ramírez Zamudio, Monica Prasad Hayes, Mona Saleh, Michael M Gaisa, Keith Sigel. Primary Anal Cancer Screening Results from 381 Women Living with HIV. J Infect Dis. 2023;227(8):932-938. PMID: 36196502.
4. Yuxin Liu, W Glenn McCluggage, Teresa M Darragh, et al. p16 Immunoreactivity Correlates with Morphological Diagnosis of HPV-associated Anal Intraepithelial Neoplasia: A study of 1,000 Biopsies. Am J Surg Pathol. 2021;45(11):1573-1578. PMID: 34231547
5. Michael M Gaisa, Keith M Sigel, Ashish A Deshmukh, Volha Lenskaya, Courtney A Chan, Richard Silvera, John Winters, Yuxin Liu. Comparing Anal Cancer Screening Algorithms Using Cytology and HPV DNA Testing in Three High-risk Populations. J Infect Dis. 2021;224(5):881-888. PMID: 33388757.
6. Yuxin Liu, Monica Prasad Hayes, Eric M. Ganz, Juan Lucas Poggio, Volha Lenskaya, Threshia Malcolm, Ashish Deshmukh, Wenxin Zheng, Keith Sigel and Michael M. Gaisa. HIV-Positive Women with Anal HSIL: A study of 153 Cases with Long-Term Anogenital Surveillance. Modern Pathology 2020;33(8):1589-1594. PMID: 32152521
7. Yuxin Liu, W Glenn McCluggage, Teresa M. Darragh, Wenxin Zheng, Jennifer M. Roberts, Kay J. Park, Pei Hui, Morgan Blakely, Keith Sigel, Michael M. Gaisa. Classifying AIN 2 Based on LAST Recommendations: Interobserver Agreement Among Experienced Pathologists. Am J Clin Pathol. 2021;18;155(6):845-852. PMID: 33210115
8. Michael Gaisa, Yuxin Liu, Ashish A. Deshmukh, Kimberly Stone, Keith Sigel. Electrocautery Ablation of Anal High-grade Squamous Intraepithelial Lesions: Effectiveness and Key Factors Associated with Outcomes. Cancer. 2020;126(7):1470-1479. PMID: 31977082
9. Yuxin Liu, Keith M Sigel, William Westra, Melissa R Gitman, Wenxin Zheng, Michael M Gaisa. HIV-infected Patients with Anal Cancer Precursors: Clinicopathological Characteristics and HPV Subtype Distribution. Dis Colon Rectum 2020;63(7):890-896. PMID: 32168092
10. Ashish A Deshmukh, Ryan Suk, Meredith S Shiels, Kalyani Sonawane, Alan G Nyitray, Yuxin Liu, Michael M Gaisa, Joel M Palefsky, Keith Sigel. Recent trends in squamous cell carcinoma of the anus incidence and mortality in the United States, 2001-2015. J Natl Cancer Inst. 2020;112(8):829-838. PMID: 31742639
Language
Position
Hospital Affiliations
- Mount Sinai Queens
- The Mount Sinai Hospital